abstract：:Blood samples from previous contrast reactors and nonreactor controls were incubated with diatrizoate and several contrast analogues. Total complement levels were assayed. All the agents caused complement activation generally proportional to their concentration. Reactors' sera responded to lower concentrations of cont...

journal_title：Investigative radiology

authors： Siegle RL,Lieberman P,Rice MC

更新日期：1983-07-01 00:00:00

abstract：:The developing trend for all medical images to be in digital form raises an important question: should diagnostic interpretations be made directly from a CRT or from some form of hard copy recording of the CRT? This question was studied by having two observers read a series of digital images of the thyroid including b...

journal_title：Investigative radiology

authors： Keyes JW Jr,Kline RC,Resinger WW,Rose EA,Koral KF,Rogers WL

更新日期：1983-05-01 00:00:00

abstract：:In order to measure the accuracy of a diagnostic imaging technique, the correctness of each observer decision must be determined. This is often difficult in clinical cases, and various strategies are frequently used to approximate the truth. Experiments using chest radiographs as an example are reported to show the pi...

journal_title：Investigative radiology

authors： Revesz G,Kundel HL,Bonitatibus M

更新日期：1983-03-01 00:00:00

abstract：:Because of a need to correlate pulmonary microvascular changes with physiologic data during lung injury, in vitro and in vivo pulmonary capillary microangiography was performed on normal dogs and those subjected to oleic acid injury and glass bead microembolization. During these studies, no significant differences wer...

journal_title：Investigative radiology

authors： Clark RL,Friedman M,Kwock L,Zaremba J

更新日期：1983-01-01 00:00:00

abstract：:The magnitude and timing of the effects of postural change on pulmonary blood flow distribution were studied in dogs by means of computed tomography (CT) and radioactive microspheres. A change in the mean attenuation values was demonstrated by CT in the anterior and posterior lung zones after change from the supine to...

journal_title：Investigative radiology

authors： Kuribayashi S,Garnic JD,Abrams HL

更新日期：1982-11-01 00:00:00

abstract：:Prior studies of the opacification-phase effects of left ventricular (LV) injection of angiographic contrast medium (CM) on LV size and function have yielded discrepant results. A sensitive ultrasonic technique was used to measure LV dimension (Di) in 10 open-chest dogs with physiologic heart rates, and injection of s...

journal_title：Investigative radiology

authors： LeWinter MM,Pavelec RS

更新日期：1982-09-01 00:00:00

abstract：:Previous work has shown that Fe3+, when administered in the proper dose and time sequence, increases the tumor uptake of gallium-67 (67Ga) while decreasing its uptake by normal tissues. The purpose of this series of experiments was to examine further the postulate that the false carrier effect is mediated at the cellu...

journal_title：Investigative radiology

authors： Stern PH,Halpern SE,Hagan PL,Chen A

更新日期：1982-07-01 00:00:00

abstract：:Arterial occlusion by direct-current transcatheter electrocoagulation (TCEC) has been developed experimentally and used successfully in clinical situations. The major shortcoming of the technique has been the lengthy time necessary for occlusion of larger arteries. In the present study we attempted to decrease the tim...

journal_title：Investigative radiology

authors： Ralston MD,Woodfield S,Halvorsen R,Pizzo SV,Thompson WM

更新日期：1982-03-01 00:00:00

abstract：:The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

journal_title：Investigative radiology

authors： Roberts JG,DiTomasso E,Webber CE

更新日期：1982-01-01 00:00:00

abstract：:We have examined the metabolic behavior of several triiodobenzoic acid derivatives because of the observed mutagenicity and cytotoxicity of 3-amino-5-acetamido-2,4,6-triiodobenzoate (I) and 3,5-diamino-2,4,6-triiodobenzoate (II). Measurements were facilitated using iodine-131 (131I)-labeled compounds. Drug retention i...

journal_title：Investigative radiology

authors： Weiss R,Hsu B,Wheeler L,Norman A,Riley RF

更新日期：1981-11-01 00:00:00

abstract：:A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...

journal_title：Investigative radiology

authors： Sorenson JA,Niklason LT,Nelson JA

更新日期：1981-07-01 00:00:00

abstract：:Because of relatively low acute toxicity, iosulamide meglumine has been recommended as an improved contrast material for intravenous cholangiography. It has been postulated that high doses of the compound could be given safely with the expectation of achieving greater biliary excretion and improved opacification of th...

journal_title：Investigative radiology

authors： Berk RN,Barnhart JL,Nazareno G,Witt BL

更新日期：1981-05-01 00:00:00

abstract：:Video dilution technique (VDT) is currently performed in conjunction with routine cerebral angiography to determine carotid blood flow in humans. Preliminary results indicate that the blood flows (as a percentage of cardial output) of the common, internal, and external carotid arteries are 8.5%, 5.5%, and 3.0%, respec...

journal_title：Investigative radiology

authors： Lantz BM,Dublin AB,McGahan JP,Link DP

更新日期：1981-05-01 00:00:00

abstract：:Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

journal_title：Investigative radiology

authors： Cuttino JT Jr,Goss FU,Clark RL,Marr MC

更新日期：1981-03-01 00:00:00

abstract：:Pyelovenous and pyelolymphatic backflow have been observed during retrograde pyelography in three patients with renal vein thrombosis. The radiographic patterns of backflow following experimental unilateral renal vein occlusion in rabbits were analyzed and correlated with the clinical findings. Capsular, perihilar, pe...

journal_title：Investigative radiology

authors： Bidgood WD Jr,Cuttino JT Jr,Clark RL,Volberg FM

更新日期：1981-01-01 00:00:00

abstract：:Biplane angiocardiography has emerged as a standard method for calculating left ventricular volume measurements. Validation of such measurements has separately been made for several projections of silicone casts of the left ventricle. This study was undertaken to establish and compare the regression lines for left ven...

journal_title：Investigative radiology

authors： Lipton MJ,Hayashi TT,Davis PL,Carlsson E

更新日期：1980-11-01 00:00:00

abstract：:In vivo and in vitro studies have shown that areas of myocardial infarctions can be delineated on CT scans after intravenous administration of iodinated contrast material to dogs with experimental myocardial infarctions. Within the first minute after intravenous administration of contrast material (initial myocardial ...

journal_title：Investigative radiology

authors： Higgins CB,Siemers PT,Newell JD,Schmidt W

更新日期：1980-11-01 00:00:00

abstract：:A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

journal_title：Investigative radiology

authors： Sovak M,Siefert HM,Ranganathan R

更新日期：1980-11-01 00:00:00

abstract：:A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...

journal_title：Investigative radiology

authors： Pitrè D,Felder E

更新日期：1980-11-01 00:00:00

abstract：:A patient, suffering a severe anaphylactoid reaction to contrast material injected for an intravenous pyelogram, developed a consumption coagulopathy and evidence of complement activation. Precontrast complement values suggested that the patient had been processing complement via the classical pathway, perhaps as a co...

journal_title：Investigative radiology

authors： Lasser EC,Lang JH,Lyon SG,Hamblin AE

更新日期：1980-11-01 00:00:00

abstract：:The cerebrovascular toxicity of three water-soluble contrast agents with a low hypertonicity (metrizamide, ioxaglate, iopamidol) was tested. Blood-brain barrier damage after carotid injection was assessed using 32P autoradiography and fluorescent microscopy after Evans blue staining. The damage to carotid endothelium ...

journal_title：Investigative radiology

authors： Gonsette RE,Liesenborgh L

更新日期：1980-11-01 00:00:00

abstract：:Experimental pulmonary arteritis was produced in rabbits by intravenous injection of alveolar macrophages from donor rabbits. These animals, along with matched controls, were studied with pulmonary angiography to test the hypothesis that angiography could detect the vasculitic process in life. The animals were then sa...

journal_title：Investigative radiology

authors： Hicken P,Hogg JC,Pare PD

更新日期：1980-07-01 00:00:00

abstract：:Gelatin encapsulated nitrogen microbubbles were effective ultrasonic contrast agents in in vitro phantom and in vivo rabbit V2 carcinoma studies. Intra-arterial injection of 80-micrometer gelatin encapsulated nitrogen microbubbles appeared to improve tumor visualization by rim enhancement, which persisted for several ...

journal_title：Investigative radiology

authors： Carroll BA,Turner RJ,Tickner EG,Boyle DB,Young SW

更新日期：1980-05-01 00:00:00

abstract：:Thoracic metastases from squamous carcinoma and adenocarcinoma of the cervix were studied by reviewing 245 consecutive cases to describe comparative incidence, natural history, and radiographic patterns. The incidence of chest metastases was higher for adenocarcinoma (20%) than for squamous carcinoma (4%). Few patient...

journal_title：Investigative radiology

authors： Sostman HD,Matthay RA

更新日期：1980-03-01 00:00:00

abstract：:Trypan blue and 197HgCl2 were used as markers of the increased leakage through the blood-brain barrier which developed after selective injection of different contrast media formulations into the internal carotid arteries of rabbits. Interest was focused on a new, experimental, nonionic medium (C-29) and possible effec...

journal_title：Investigative radiology

authors： Golman K

更新日期：1979-07-01 00:00:00

abstract：:We present a new method for evaluating in vivo changes in bone mineralization in the peripheral skeleton, using computed tomography (CT). A set of bone mineralization indices are generated from numerous CT images of the patient's distal radius. The cross-sectional anatomy displayed by the CT scan allows for separate e...

journal_title：Investigative radiology

authors： Orphanoudakis SC,Jensen PS,Rauschkolb EN,Lang R,Rasmussen H

更新日期：1979-03-01 00:00:00

abstract：:The application of intravenous, intrathecal, and inhalation enhancement techniques to the CT evaluation of the nonhuman primate (Papio cynocephalus/anubis) is described. The falx cerebri cortical vasculature, vein of Galen, straight sinus and tentorium cerebelli were defined with intravenous enhancement. Intrathecal C...

journal_title：Investigative radiology

authors： Drayer BP,Wolfson SK Jr,Rosenbaum AE,Dujovny M,Boehnke M,Cook EE

更新日期：1979-01-01 00:00:00

abstract：:The effects of edge gradient and blur on the detection pulmonary nodules were studied, using a test series of 175 artificial nodules on 30 chest films. The nodules were of homogeneous texture, about 1 cm in diameter and had a mean contrast of .12. Six observers viewed the film set, scoring both location and confidence...

journal_title：Investigative radiology

authors： Kundel HL,Revesz G,Toto L

更新日期：1979-01-01 00:00:00

abstract：:Lymphangiograms of canine cardiac and pulmonary efferent mediastinal lymphatics were made by cannulation and injection of Ethiodol. Injections were made singly and serially. The mediastinal lymphatics and lymph nodes, which constitute the pathways of drainage of the heart and lungs, were delineated from the point of c...

journal_title：Investigative radiology

authors： Leeds SE,Uhley HN,Meister RB

更新日期：1979-01-01 00:00:00

abstract：:Gastrografin and Amipaque with identical iodine content and flavoring were orally administered in 100 ml doses to 10 healthy volunteers in a double-blind crossover study. The nonionic Amipaque has only about one third of the osmolality of Gastrografin, and draws less fluid into the bowel lumen. Consequently there is l...

journal_title：Investigative radiology

authors： Johansen JG

更新日期：1978-11-01 00:00:00

abstract：:Comparatively new in the roentgen evaluation of infants and children, xerography would appear to be ideal for portraying the pediatric airway. Since the radiation dose of xerography is higher than conventional radiography, its image quality is the subject of careful scrutiny in a pediatric setting here described in 23...

journal_title：Investigative radiology

authors： Scott JR,Kramer SS,Griscom NT

更新日期：1978-07-01 00:00:00

abstract：:A feasibility study is described to provide quantitative texture measures to distinguish between normal lung, alveolar infiltrates and interstitial infiltrates. Advanced computer imaging technology and decision making processes were applied to distinguish between these textural patterns. The results, based on computer...

journal_title：Investigative radiology

authors： Tully RJ,Conners RW,Harlow CA,Lodwick GS

更新日期：1978-07-01 00:00:00

abstract：:The purpose of our investigation was to determine whether iopanoyl glucuronide, the major metabolite of iopanoic acid (Telepaque), undergoes hydrolysis by bacterial beta-glucuronidase in dogs. The conjugated compound was identified and quantitated by elemental analysis, fluorescent excitation analysis, thin-layer chro...

journal_title：Investigative radiology

authors： Thoeni RF,Goldberg HI,Moss AA,Lin SK,Brito AC

更新日期：1978-05-01 00:00:00

abstract：:The feasibility of control of traumatic hepatic hemorrhage by angiographic transcatheter embolization was investigated. Bleeding sites were created in the livers of each of twelve dogs, and the hepatic artery was occluded with Gelfoam. Successful control of bleeding was demonstrated by postembolization angiography in ...

journal_title：Investigative radiology

authors： Tyler T,Rosenbaum HD

更新日期：1978-01-01 00:00:00

abstract：:Renal arteriography gives a reliable anatomic delineation of the renal vasculature. However, the presence of renal arterial disease does not determine the physiologic significance of the lesion. The intravenous infusion of saralasin, a specific angiotensin II antagonist, has been investigated as a method for identify...

journal_title：Investigative radiology

authors： Tegtmeyer CJ,Latour EA,Vaughan ED Jr,Ayers CR,Carey RM,Wellons HA Jr

更新日期：1977-11-01 00:00:00

abstract：:The efficacy and safety of perfluoroctylbromide as a diagnostic contrast agent for direct lymphography was studied in mongrel dogs. This radiopaque perfluorocarbon has several advantages over Ethiodol. The liquid compound has injection times one-fifth of that required for Ethiodol. When dosages were three to four tim...

journal_title：Investigative radiology

authors： Liebner EJ

更新日期：1977-07-01 00:00:00

abstract：:Three methods are presented which provide statistically acceptable estimates of mean transit time of opacified blood during angiography. While the methods vary in precision, the selection of the method appropriate for any particular experimental model depends on the degree of precision required to demonstrate the effe...

journal_title：Investigative radiology

authors： Silverman NR,Rosen L

更新日期：1977-07-01 00:00:00

abstract：:A method is presented for selective catheterization and filming of the small internal spermatic and proper hepatic arteries in rabbits. The angiograms thus obtained afford clear delineation of the vessels and their branches and can enhance radiographic investigation of a variety of experimental disease models. ...

journal_title：Investigative radiology

authors： Young S,Hollenberg NK

更新日期：1977-05-01 00:00:00

abstract：:Twenty-six patients who had received 43 grafts were studied before and after coronary artery vein bypass surgery. Cine ventriculograms taken in the right anterior oblique projection were analyzed and regional ejection fractions calculated. Single and multiple grafts were considered separately as were thrombosed and pa...

journal_title：Investigative radiology

authors： Martin EC,Wixson D,Baltaxe HA

更新日期：1977-05-01 00:00:00

abstract：:Using simple surgical techniques, experimental carotid aneurysms are created which simulate some types of human berry aneurysms, both in hemodynamic and radiographic behavior. End to side anastomoses of an external jugular vein graft to the common carotid artery can be carried out by radiologic personnel with no forma...

journal_title：Investigative radiology

authors： Kerber CW,Buschman RW

更新日期：1977-03-01 00:00:00